p53 [ac Lys370] Antibody (S06-7C9)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-20027

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-20027-100ul
NBP3-20027-50ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S06-7C9

Concentration

0.3 mg/ml

View all p53 Antibodies »

Product Specifications

Immunogen

A synthetic acetyl-peptide corresponding to residues surrounding Lys370 of human p53 (Uniprot # P04637)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

53 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for p53 [ac Lys370] Antibody (S06-7C9)

Western Blot: p53 [ac Lys370] Antibody (S06-7C9) [NBP3-20027] - Western blot detection of p53 in Rat Brain lysates using NBP3-20027 (1:1000 diluted). Predicted band size: 44kDa. Observed band size: 53kDa.

Applications for p53 [ac Lys370] Antibody (S06-7C9)

Application
Recommended Usage

Western Blot

1/1000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: p53

p53 is a stress-regulated transcription factor that was first identified as an SV40 large T antigen-binding protein. It plays a major role in the cellular response to DNA damage and other genomic aberrations. The activation of p53 can lead to either cell cycle arrest and DNA repair, or apoptosis. p53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro. Mutation of p53 is the most common genetic change so far identified in a number of major carcinomas. This antibody can be used for the specific detection of human p53 that is synthesized in the presence of p53 from other species.

Alternate Names

BCC7, LFS1, TP53, TRP53

Gene Symbol

TP53

Additional p53 Products

Product Documents for p53 [ac Lys370] Antibody (S06-7C9)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for p53 [ac Lys370] Antibody (S06-7C9)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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