p57 Kip2 Antibody (KIP2/7187) [Janelia Fluor® 646]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-20895JF646

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

Immunohistochemistry-Paraffin

Label

Janelia Fluor 646

Antibody Source

Monoclonal Mouse IgG Kappa Clone # KIP2/7187

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all p57 Kip2 Antibodies »

Product Summary for p57 Kip2 Antibody (KIP2/7187) [Janelia Fluor® 646]

Immunogen

Recombinant full-length human p57 Kip2 protein

Localization

Nucleus.

Specificity

Recognizes a protein of 57kDa, identified as p57 Kip2 It shows no cross-reaction with p27Kip1

Clonality

Monoclonal

Host

Mouse

Isotype

IgG Kappa

Applications for p57 Kip2 Antibody (KIP2/7187) [Janelia Fluor® 646]

Application
Recommended Usage

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: p57 Kip2

p57kip2 is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate.

Alternate Names

Beckwith-Wiedemann syndrome, BWS, cyclin-dependent kinase inhibitor 1C, cyclin-dependent kinase inhibitor 1C (p57, Kip2), Cyclin-dependent kinase inhibitor p57, KIP2BWCR, p57, p57Kip2, WBS

Gene Symbol

CDKN1C

Additional p57 Kip2 Products

Product Documents for p57 Kip2 Antibody (KIP2/7187) [Janelia Fluor® 646]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for p57 Kip2 Antibody (KIP2/7187) [Janelia Fluor® 646]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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