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p57 Kip2 Antibody (SR2016)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21646

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21646-100ul
NBP3-21646-50ul

Key Product Details

Validated by

Biological Validation

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR2016

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for p57 Kip2 Antibody (SR2016)

Immunogen

A synthesized peptide derived from human p57 Kip2 (Uniprot #: P49918)

Specificity

Detects endogenous levels of total p57 Kip2

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

57 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for p57 Kip2 Antibody (SR2016)

Immunocytochemistry/Immunofluorescence: p57 Kip2 Antibody (SR2016) [NBP3-21646] -

Immunocytochemistry/Immunofluorescence: p57 Kip2 Antibody (SR2016) [NBP3-21646] - Immunofluorescent analysis of HeLa cells treated with dexamethasone, using NBP3-21646.

Western Blot: p57 Kip2 Antibody (SR2016) [NBP3-21646] -

Western Blot: p57 Kip2 Antibody (SR2016) [NBP3-21646] - Western blot analysis on HeLa cell using NBP3-21646.

Immunohistochemistry: p57 Kip2 Antibody (SR2016) [NBP3-21646] -

Immunohistochemistry: p57 Kip2 Antibody (SR2016) [NBP3-21646] - Immunohistochemical analysis of paraffin-embedded rat kidney, using NBP3-21646.

Applications for p57 Kip2 Antibody (SR2016)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Immunohistochemistry

1:50-1:200

Immunoprecipitation

1:50

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: p57 Kip2

p57kip2 is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate.

Alternate Names

Beckwith-Wiedemann syndrome, BWS, cyclin-dependent kinase inhibitor 1C, cyclin-dependent kinase inhibitor 1C (p57, Kip2), Cyclin-dependent kinase inhibitor p57, KIP2BWCR, p57, p57Kip2, WBS

Gene Symbol

CDKN1C

Additional p57 Kip2 Products

Product Documents for p57 Kip2 Antibody (SR2016)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for p57 Kip2 Antibody (SR2016)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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