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p57 Kip2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-27877

Novus Biologicals, part of Bio-Techne
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NBP3-27877

Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Format

BSA Free

Concentration

1 mg/ml

Product Specifications

Immunogen

p57 Kip2 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human p57 Kip2. The immunogen is located within amino acids 40 - 90 of p57 Kip2.

Specificity

At least three isoforms of p57 Kip2 are known to exist; this antibody will detect all three isoforms. Despite its predicted molecular weight, p57 Kip2 often migrates at 57kDa in SDS-PAGE. CDKN1C antibody is predicted to not cross react with other CIP/KIP proteins.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for p57 Kip2 Antibody - BSA Free

p57 Kip2 Antibody

Western Blot: p57 Kip2 Antibody [NBP3-27877] -

Western Blot: p57 Kip2 Antibody [NBP3-27877] - Western blot analysis of p57 Kip2 in 293 cell lysate with p57 Kip2 antibody at (A) 1 and (B) 2 u/mL.
p57 Kip2 Antibody

Immunocytochemistry/ Immunofluorescence: p57 Kip2 Antibody [NBP3-27877] -

Immunocytochemistry/ Immunofluorescence: p57 Kip2 Antibody [NBP3-27877] - Immunofluorescence of p57 Kip2 in 293 cells with p57 Kip2 antibody at 20 u/mL.

Applications for p57 Kip2 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

20 ug/mL

Western Blot

1 - 2 ug/mL

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: p57 Kip2

p57kip2 is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate.

Alternate Names

Beckwith-Wiedemann syndrome, BWS, cyclin-dependent kinase inhibitor 1C, cyclin-dependent kinase inhibitor 1C (p57, Kip2), Cyclin-dependent kinase inhibitor p57, KIP2BWCR, p57, p57Kip2, WBS

Gene Symbol

CDKN1C

UniProt

Additional p57 Kip2 Products

Product Documents for p57 Kip2 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for p57 Kip2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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