p63/TP73L Antibody (87C553)

Novus Biologicals, part of Bio-Techne | Catalog # NB100-56549

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Validated:

Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 87C553

Concentration

0.5 mg/ml

View all p63/TP73L Antibodies »

Product Specifications

Immunogen

This antibody was developed against a synthetic peptide corresponding to human p63. This peptide immunogen sequence corresponds to: (1) Amino acids 67-84 of p63 alpha (AAG45607.1); (2) Amino acids 28-45 of p63 beta ( AAC62637.1); (3) Amino acids 28-45 of p63 gamma (AAC62633.1) and (4) Amino acids 28-45 of p63 delta (AAF43489.1). CSVQPIDLNFVDEPSEDG

Specificity

The p63 was developed against a peptide sequence that is 100% conserved between the alpha, beta, gamma, and delta isoforms of p63.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Description

This Product is Only Available For Sale Outside of USA. Optimal dilution of this antibody should be experimentally determined.

Scientific Data Images for p63/TP73L Antibody (87C553)

Western Blot: p63/TP73L Antibody (87C553) [NB100-56549]

Western Blot: p63/TP73L Antibody (87C553) [NB100-56549]

Western Blot: TP63 Antibody (87C553) [NB100-56549] - analysis of p63 in mouse 1) placenta and 2) thymus using antibody at 3 ug/ml.
Western Blot: p63/TP73L Antibody (87C553) [NB100-56549]

Western Blot: p63/TP73L Antibody (87C553) [NB100-56549]

Western Blot: TP63 Antibody (87C553) [NB100-56549] - analysis of p63 in A549 lysate using p63 antibody at 3 ug/ml.

Applications for p63/TP73L Antibody (87C553)

Application
Recommended Usage

Western Blot

1:100-1:167
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

0.2 ml PBS and 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: p63/TP73L

This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined

Long Name

Tumor Protein 63

Alternate Names

EEC3, KET, OFC8, p40, p51, p73L, SHFM4, TP63, TP73L

Entrez Gene IDs

8626 (Human)

Gene Symbol

TP63

UniProt

Q9H3D4

Additional p63/TP73L Products

Product Documents for p63/TP73L Antibody (87C553)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for p63/TP73L Antibody (87C553)

This Product is Only Available For Sale Outside of USA. Optimal dilution of this antibody should be experimentally determined.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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