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p63/TP73L Antibody (rP40/8765)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-20374

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Mouse IgG2a Kappa Clone # rP40/8765

Concentration

0.2 mg/ml

Product Specifications

Immunogen

Recombinant fragment (around aa1-200) of human p63/TP73L protein (exact sequence is proprietary)

Localization

Nucleus.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Description

Positive Controls: Human prostate, lung or bladder squamous cell carcinoma tissue.

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C. Non-hazardous. No MSDS required.

Scientific Data Images for p63/TP73L Antibody (rP40/8765)

p63/TP73L Antibody (rP40/8765) p63/TP73L Antibody (rP40/8765) - Azide and BSA Free

p63/TP73L Antibody (rP40/8765) - Azide and BSA Free

Formalin-fixed, paraffin-embedded human prostate cancer stained with p63 Recombinant Mouse Monoclonal Antibody (rP40/8765). HIER: Tris/EDTA, pH9.0, 45min. 2: HRP-polymer, 30min. DAB, 5min.

Applications for p63/TP73L Antibody (rP40/8765)

Application
Recommended Usage

Immunohistochemistry-Paraffin

1-2 ug/ml
Application Notes
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes. at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.

Optimal dilution for a specific application should be determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

10mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: p63/TP73L

The p63 gene, a homologue of the tumor suppressor p53, is highly expressed in the basal or progenitor layers of many epithelial tissues. P63 shows remarkable structural similarity to p53 and to the related p73 gene. Unlike p53, the p63 gene encodes multiple isotypes with remarkably divergent abilities to transactivate p53 reporter genes and induce apoptosis.

Long Name

Tumor Protein 63

Alternate Names

EEC3, KET, OFC8, p40, p51, p73L, SHFM4, TP63, TP73L

Gene Symbol

TP63

Additional p63/TP73L Products

Product Documents for p63/TP73L Antibody (rP40/8765)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for p63/TP73L Antibody (rP40/8765)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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