p63/TP73L Antibody (TP63/11)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-07431

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # TP63/11

Concentration

0.2 mg/ml

View all p63/TP73L Antibodies »

Product Summary for p63/TP73L Antibody (TP63/11)

Immunogen

Recombinant full-length human p63/TP73L protein (Uniprot: Q9H3D4)

Localization

Nuclear

Marker

Squamous, Basal & Myoepithelial Cell Marker

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Theoretical MW

63 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP3-08667)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.

Scientific Data Images for p63/TP73L Antibody (TP63/11)

Immunohistochemistry-Paraffin: p63/TP73L Antibody (TP63/11) [NBP3-07431]

Immunohistochemistry-Paraffin: p63/TP73L Antibody (TP63/11) [NBP3-07431]

Immunohistochemistry-Paraffin: p63/TP73L Antibody (TP63/11) [NBP3-07431] - Formalin-fixed, paraffin-embedded Mouse Prostate stained with p63/TP73L Mouse Monoclonal Antibody (TP63/11).
Immunohistochemistry-Paraffin: p63/TP73L Antibody (TP63/11) [NBP3-07431]

Immunohistochemistry-Paraffin: p63/TP73L Antibody (TP63/11) [NBP3-07431]

Immunohistochemistry-Paraffin: p63/TP73L Antibody (TP63/11) [NBP3-07431] - Formalin-fixed, paraffin-embedded human Prostate Cancer stained with p63/TP73L Mouse Monoclonal Antibody (TP63/11).

Applications for p63/TP73L Antibody (TP63/11)

Application
Recommended Usage

Immunohistochemistry-Paraffin

0.25-0.5 ug/ml
Application Notes
Immunohistochemistry (Formalin-fixed): 0.25-0.5ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.
Optimal dilution for a specific application should be determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: p63/TP73L

The p63 gene, a homologue of the tumor suppressor p53, is highly expressed in the basal or progenitor layers of many epithelial tissues. P63 shows remarkable structural similarity to p53 and to the related p73 gene. Unlike p53, the p63 gene encodes multiple isotypes with remarkably divergent abilities to transactivate p53 reporter genes and induce apoptosis.

Long Name

Tumor Protein 63

Alternate Names

EEC3, KET, OFC8, p40, p51, p73L, SHFM4, TP63, TP73L

Gene Symbol

TP63

UniProt

Q9H3D4

Additional p63/TP73L Products

Product Documents for p63/TP73L Antibody (TP63/11)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for p63/TP73L Antibody (TP63/11)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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