PAK1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-19680

Novus Biologicals, part of Bio-Techne
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NBP2-19680
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PAK1 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human PAK1. The exact sequence is proprietary.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Zebrafish (84%), Xenopus Laevis (84%).

Localization

Cytoplasm; Cell junction; focal adhesion

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

61 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PAK1 Antibody

Western Blot: PAK1 Antibody [NBP2-19680]

Western Blot: PAK1 Antibody [NBP2-19680]

Western Blot: PAK1 Antibody [NBP2-19680] - Whole cell extracts (30 ug) was separated by 7.5% SDS-PAGE, and the membrane was blotted with PAK1 antibody diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: PAK1 Antibody [NBP2-19680]

Immunocytochemistry/ Immunofluorescence: PAK1 Antibody [NBP2-19680]

Immunocytochemistry/Immunofluorescence: PAK1 Antibody [NBP2-19680] - Immunofluorescence analysis of methanol-fixed A431, using antibody at 1:500 dilution.
Immunohistochemistry-Paraffin: PAK1 Antibody [NBP2-19680]

Immunohistochemistry-Paraffin: PAK1 Antibody [NBP2-19680]

Immunohistochemistry-Paraffin: PAK1 Antibody [NBP2-19680] - Paraffin-embedded mouse fore brain. PAK1 antibody [N2C2], Internal dilution: 1:500.
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Applications for PAK1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

10 - 1:500

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:10000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: PAK1

PAK proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. These proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK1 regulates cell motility and morphology. Alternativelt spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Long Name

p21/Cdc42/Rac1-activated Kinase 1

Alternate Names

alpha-PAK

Gene Symbol

PAK1

UniProt

Q13153

Additional PAK1 Products

Product Documents for PAK1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for PAK1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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