Parkin Antibody (1H4)

Novus Biologicals, part of Bio-Techne | Catalog # H00005071-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG3 Kappa Clone # 1H4

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Parkin Antibodies »

Product Specifications

Immunogen

PARK2 (AAH22014, 288 a.a. ~ 387 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. PCVGTGDTVVLRGALGGFRRGVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGYGQRRTK

Specificity

PARK2 - Parkinson disease (autosomal recessive, juvenile) 2, parkin

Clonality

Monoclonal

Host

Mouse

Isotype

IgG3 Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for Parkin Antibody (1H4)

Western Blot: Parkin Antibody (1H4) [H00005071-M01]

Western Blot: Parkin Antibody (1H4) [H00005071-M01]

Western Blot: Parkin Antibody (1H4) [H00005071-M01] - Parkin monoclonal antibody (M01), clone 1H4. Western Blot analysis of Parkin expression in PC-12.
Immunocytochemistry/ Immunofluorescence: Parkin Antibody (1H4) [H00005071-M01]

Immunocytochemistry/ Immunofluorescence: Parkin Antibody (1H4) [H00005071-M01]

Immunocytochemistry/Immunofluorescence: Parkin Antibody (1H4) [H00005071-M01] - Analysis of monoclonal antibody to PARK2 on HeLa cell. Antibody concentration 10 ug/ml.
Western Blot: Parkin Antibody (1H4) [H00005071-M01]

Western Blot: Parkin Antibody (1H4) [H00005071-M01]

Western Blot: Parkin Antibody (1H4) [H00005071-M01] - PARK2 monoclonal antibody (M01), clone 1H4 Analysis of PARK2 expression in Jurkat.
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Applications for Parkin Antibody (1H4)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for IF and ELISA.

Reviewed Applications

Read 2 reviews rated 3.5 using H00005071-M01 in the following applications:

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Parkin

The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support.

Long Name

Parkinson Disease [autosomal recessive, juvenile] 2, Parkin [PARK2], transcript variant 1

Alternate Names

AR-JP, PARK2, PDJ, PRKN

Entrez Gene IDs

5071 (Human)

Gene Symbol

PRKN

OMIM

211980 (Human)

UniProt

AAH22014 (Human)

Additional Parkin Products

Product Documents for Parkin Antibody (1H4)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Parkin Antibody (1H4)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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