Pax3 Antibody (PAX3/8426) [DyLight 755]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-20757IR

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin

Label

DyLight 755 (Excitation = 754 nm, Emission = 776 nm)

Antibody Source

Monoclonal Mouse IgG Clone # PAX3/8426

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Pax3 Antibodies »

Product Specifications

Immunogen

Recombinant human Pax3 protein

Localization

Nucleus.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG

Applications for Pax3 Antibody (PAX3/8426) [DyLight 755]

Application
Recommended Usage

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Pax3

PAX3 is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These proteins play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.

Long Name

Paired Box Gene 3 [Waardenburg Syndrome 1]

Alternate Names

HUP2, WS1

Gene Symbol

PAX3

Additional Pax3 Products

Product Documents for Pax3 Antibody (PAX3/8426) [DyLight 755]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Pax3 Antibody (PAX3/8426) [DyLight 755]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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