Pax5/BSAP Antibody (PAX5/3977R) [DyLight 488]

DyLight 488 (Excitation = 493 nm, Emission = 518 nm)

Recombinant Monoclonal Rabbit IgG Clone # PAX5/3977R

Please see the vial label for concentration. If unlisted please contact technical services.

A recombinant fragment (around aa 235-382) of human PAX5 protein (exact sequence is proprietary) (Uniprot: Q02548)

Nuclear

The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 21,000, full-length human proteins. The PAX5 gene is a member of the paired box (PAX)family of transcription factors. The central feature of this gene family is a novel, highly conservedDNA-binding domain, known as the paired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute toneoplastic transformation. The PAX5 gene encodes theB-celllineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis; therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis.

Early B-Cell Marker

Monoclonal

Rabbit

IgG

Protein A or G purified

50mM Sodium Borate

0.05% Sodium Azide

Please see the vial label for concentration. If unlisted please contact technical services.

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Store at 4C in the dark.