PBR Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-45769

Novus Biologicals, part of Bio-Techne
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NBP1-45769-0.025mg
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Human, Mouse, Rat

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

IF/IHC, Immunohistochemistry, Immunohistochemistry-Frozen

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all PBR Antibodies »

Product Specifications

Immunogen

Synthetic peptide surrounding amino acid 81 of mouse PBR (BAA04749).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This product is manufactured by Abcam and distributed by Novus Biologicals. (Abcam Catalog Number: ab2305)

Scientific Data Images for PBR Antibody

Western Blot: PBR Antibody [NBP1-45769]

Western Blot: PBR Antibody [NBP1-45769]

Western Blot: PBR Antibody [NBP1-45769] - Analysis of PBRexpression using:Lane 1: Jurkat cell lysateLane 2: Recombinant PBRLane 3: Rat kidney tissue lysate

Applications for PBR Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

10-20 ug/ml

Western Blot

0.5-4 ug/ml

Reviewed Applications

Read 1 review rated 3 using NBP1-45769 in the following applications:

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2), 0.5% BSA, 30% Glycerol

Preservative

0.01% Thimerosal

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: PBR

PBR (Peripheral-type Benzodiazepine Receptor) is a ubiquitous protein (18 kDa) found in most steroidogenic tissues. It is located primarily in the outer mitochondrial membrane of steroid-producing tissues and is found in association with a 34 kDa voltage-dependent anion channel protein (VDAC). PBR is involved in the regulation of cholesterol transport from the outer to the inner mitochondrial membrane. It is thought to be part of the mitochondrial permeability transition pore (PT) and to be involved in apoptosis.

Long Name

Peripheral-type Benzodiazepine Receptor

Alternate Names

TSPO

Entrez Gene IDs

706 (Human); 12257 (Mouse); 24230 (Rat)

Gene Symbol

TSPO

UniProt

BAA04749 (Mouse)

Additional PBR Products

Product Documents for PBR Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for PBR Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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