PCDHB2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-30922

Novus Biologicals, part of Bio-Techne
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NBP2-30922
NBP2-30922-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PCDHB2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: ESITPGTTFLIERAQDLDVGTNSLQNYTISPNFHFHLNLQDSLDGIILPQLVLNRALDREEQPEIRLTLTALDGGSPPRSGTALVRIEVV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PCDHB2 Antibody

Immunocytochemistry/ Immunofluorescence: PCDHB2 Antibody [NBP2-30922]

Immunocytochemistry/ Immunofluorescence: PCDHB2 Antibody [NBP2-30922]

Immunocytochemistry/Immunofluorescence: PCDHB2 Antibody [NBP2-30922] - Immunofluorescent staining of human cell line RH-30 shows localization to nucleoplasm.
Immunohistochemistry-Paraffin: PCDHB2 Antibody [NBP2-30922]

Immunohistochemistry-Paraffin: PCDHB2 Antibody [NBP2-30922]

Immunohistochemistry-Paraffin: PCDHB2 Antibody [NBP2-30922] - Staining in human testis and pancreas tissues using anti-PCDHB2 antibody. Corresponding PCDHB2 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: PCDHB2 Antibody [NBP2-30922]

Immunohistochemistry-Paraffin: PCDHB2 Antibody [NBP2-30922]

Immunohistochemistry-Paraffin: PCDHB2 Antibody [NBP2-30922] - Staining of human cerebral cortex shows moderate positivity in subsets of glial cells.
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Applications for PCDHB2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PCDHB2

PCDHB2 is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. [provided by RefSeq]

Alternate Names

MGC111392, PCDH-BETA2, PCDH-beta-2, protocadherin beta 2, protocadherin beta-2

Gene Symbol

PCDHB2

UniProt

Q9Y5E7 (Human)

Additional PCDHB2 Products

Product Documents for PCDHB2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PCDHB2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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