PCYT1B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86563

Novus Biologicals, part of Bio-Techne
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NBP1-86563
NBP1-86563-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (95%), Rat (96%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PCYT1B Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: PVVTTDAESETGIPKSLSNEPPSETMEEIEHTCPQPRLTLTAPAPFADETNCQCQAPHEKLTIAQARLGTPADRPVRVYADGIFDLFHSGHARALMQAKTLFPNSYLLVGV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PCYT1B Antibody

Immunohistochemistry-Paraffin: PCYT1B Antibody [NBP1-86563]

Immunohistochemistry-Paraffin: PCYT1B Antibody [NBP1-86563]

Immunohistochemistry-Paraffin: PCYT1B Antibody [NBP1-86563] - Staining of human liver shows strong cytoplasmic positivity with granular pattern in hepatocytes.

Applications for PCYT1B Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PCYT1B

TCP1 beta is a subunit of a cytosolic hetero-oligomer chaperon that is known to be involved in the folding of actin and tubulin. This protein is a member of the chaperonin family, which includes Escherichia coli GroEL, the mitochondrial heat-shock protein Hsp60, the plastid Rubisco-subunit-binding protein and the archaebacterial protein TF55. These chaperonins assist the folding of proteins upon ATP hydrolysis. Nine different subunits of TCP-1 containing chaperonin complexes from mammalian testis and seven different subunits of mouse F9 cells have been identified. It has been suggested that each CCT subunit has a specific, independent function, as they are highly diverged from each other but conserved from mammals to yeast. The expansion in the number of types of CCT subunit, compared with other chaperonins, has allowed CCT to carry out more complex functions that are required for the folding and assembly of highly evolved eukaryotic proteins.

Alternate Names

CCT B, CCTB, CCT-betaEC 2.7.7.15, choline-phosphate cytidylyltransferase B, CT B, CTB, CTP:phosphocholine cytidylyltransferase B, EC 2.7.7, phosphate cytidylyltransferase 1, choline, beta, phosphate cytidylyltransferase 1, choline, beta isoform, Phosphorylcholine transferase B

Gene Symbol

PCYT1B

Additional PCYT1B Products

Product Documents for PCYT1B Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PCYT1B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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