PDCD4 Antibody (4C2) [PE]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-18224PE

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Product Datasheet / COA / SDS

View Available Conjugates

Conjugate

Catalog #

Unconjugated

NBP3-18224

Alexa Fluor 350

NBP3-18224AF350

Alexa Fluor 405

NBP3-18224AF405

Alexa Fluor 488

NBP3-18224AF488

Alexa Fluor 532

NBP3-18224AF532

Alexa Fluor 594

NBP3-18224AF594

Alexa Fluor 647

NBP3-18224AF647

Alexa Fluor 700

NBP3-18224AF700

Alexa Fluor 750

NBP3-18224AF750

Allophycocyanin

NBP3-18224APC

Biotin

NBP3-18224B

CoraFluor 1

NBP3-18224CL1

DyLight 350

NBP3-18224UV

DyLight 405

NBP3-18224V

DyLight 488

NBP3-18224G

DyLight 550

NBP3-18224R

DyLight 594

NBP3-18224DL594

DyLight 650

NBP3-18224C

DyLight 680

NBP3-18224FR

DyLight 755

NBP3-18224IR

FITC

NBP3-18224F

HRP

NBP3-18224H

Janelia Fluor 525

NBP3-18224JF525

Janelia Fluor 549

NBP3-18224JF549

Janelia Fluor 585

NBP3-18224JF585

Janelia Fluor 635

NBP3-18224JF635

Janelia Fluor 646

NBP3-18224JF646

Janelia Fluor 669

NBP3-18224JF669

mFluor Violet 450 SE

NBP3-18224MFV450

mFluor Violet 500 SE

NBP3-18224MFV500

mFluor Violet 610 SE

NBP3-18224MFV610

PerCP

NBP3-18224PCP

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

PE (Excitation = 488 nm, Emission = 575 nm)

Antibody Source

Monoclonal Mouse IgG₁ kappa Clone # 4C2

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all PDCD4 Antibodies »

Product Specifications

Immunogen

Recombinant human PDCD4 (1-469aa) purified from E. coli

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁ kappa

Applications for PDCD4 Antibody (4C2) [PE]

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: PDCD4

Programmed cell death 4 (Pdcd4) is a novel tumor suppressor. Pdcd4 directly inhibits the helicase activity of eukaryotic translation initiation factor 4A (eIF4A), a component of the translation initiation complex. Pdcd4 also suppresses the transactivation of activator protein-1 (AP-1)-responsive promoters by c-Jun. Pdcd4 contains two Akt phosphorylation sites, one at Ser67 and the other at Ser457. The phosphorylation of Pdcd4 by Akt causes nuclear translocation of Pdcd4 and a significant decrease in the ability of Pdcd4 to interfere with the transactivation of AP-1 responsive promoters by c-Jun.

Long Name

Programmed Cell Death 4

Alternate Names

H731, Protein 197/15a

Gene Symbol

PDCD4

Additional PDCD4 Products

Product Documents for PDCD4 Antibody (4C2) [PE]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for PDCD4 Antibody (4C2) [PE]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews

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