PDCD4 Antibody (k4C1) [Biotin]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-04329B

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NBP1-04329AF350

Alexa Fluor 405

NBP1-04329AF405

Alexa Fluor 488

NBP1-04329AF488

Alexa Fluor 532

NBP1-04329AF532

Alexa Fluor 594

NBP1-04329AF594

Alexa Fluor 647

NBP1-04329AF647

Alexa Fluor 700

NBP1-04329AF700

Alexa Fluor 750

NBP1-04329AF750

CoraFluor 1

NBP1-04329CL1

DyLight 350

NBP1-04329UV

DyLight 405

NBP1-04329V

DyLight 488

NBP1-04329G

DyLight 550

NBP1-04329R

DyLight 594

NBP1-04329DL594

DyLight 650

NBP1-04329C

DyLight 680

NBP1-04329FR

DyLight 755

NBP1-04329IR

FITC

NBP1-04329F

HRP

NBP1-04329H

Janelia Fluor 525

NBP1-04329JF525

Janelia Fluor 549

NBP1-04329JF549

Janelia Fluor 585

NBP1-04329JF585

Janelia Fluor 635

NBP1-04329JF635

Janelia Fluor 646

NBP1-04329JF646

Janelia Fluor 669

NBP1-04329JF669

mFluor Violet 450 SE

NBP1-04329MFV450

mFluor Violet 500 SE

NBP1-04329MFV500

mFluor Violet 610 SE

NBP1-04329MFV610

Forumulation

Catalog #

BSA Free

NBP1-04329

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Biotin

Antibody Source

Monoclonal Mouse IgG₁ kappa Clone # k4C1

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all PDCD4 Antibodies »

Product Specifications

Immunogen

Recombinant human PDCD4 (1-469aa) purified from E. coli (NP_055271).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁ kappa

Applications for PDCD4 Antibody (k4C1) [Biotin]

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: PDCD4

Programmed cell death 4 (Pdcd4) is a novel tumor suppressor. Pdcd4 directly inhibits the helicase activity of eukaryotic translation initiation factor 4A (eIF4A), a component of the translation initiation complex. Pdcd4 also suppresses the transactivation of activator protein-1 (AP-1)-responsive promoters by c-Jun. Pdcd4 contains two Akt phosphorylation sites, one at Ser67 and the other at Ser457. The phosphorylation of Pdcd4 by Akt causes nuclear translocation of Pdcd4 and a significant decrease in the ability of Pdcd4 to interfere with the transactivation of AP-1 responsive promoters by c-Jun.

Long Name

Programmed Cell Death 4

Alternate Names

H731, Protein 197/15a

Entrez Gene IDs

27250 (Human)

Gene Symbol

PDCD4

UniProt

Q53EL6 (Human)

Additional PDCD4 Products

Product Documents for PDCD4 Antibody (k4C1) [Biotin]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for PDCD4 Antibody (k4C1) [Biotin]

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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