PDE11A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-32910

Novus Biologicals, part of Bio-Techne
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NBP1-32910
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PDE11A Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human PDE11A. The exact sequence is proprietary.

Localization

Cytoplasm, cytosol

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PDE11A Antibody

Western Blot: PDE11A Antibody [NBP1-32910]

Western Blot: PDE11A Antibody [NBP1-32910]

Western Blot: PDE11A Antibody [NBP1-32910] - Sample (30 ug of whole cell lysate) A: Hep G2 5% SDS PAGE; antibody diluted at 1:5000.
Immunohistochemistry-Paraffin: PDE11A Antibody [NBP1-32910]

Immunohistochemistry-Paraffin: PDE11A Antibody [NBP1-32910]

Immunohistochemistry-Paraffin: PDE11A Antibody [NBP1-32910] - Paraffin-embedded SAS xenograft, using antibody at 1:500 dilution.
Western Blot: PDE11A Antibody [NBP1-32910]

Western Blot: PDE11A Antibody [NBP1-32910]

Western Blot: PDE11A Antibody [NBP1-32910] - Analysis of PDE11A on NIH-3T3 lysate using NBP1-32910 at a dilution of 1:1000. 30ug of whole cell lysate loaded on 7.5% SDS PAGE gel.

Applications for PDE11A Antibody

Application
Recommended Usage

Immunohistochemistry

10 - 1:500

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:1000-1:10000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: PDE11A

The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.

Long Name

Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A

Alternate Names

EC 3.1.4.35, EC 3.1.4.53

Gene Symbol

PDE11A

Additional PDE11A Products

Product Documents for PDE11A Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PDE11A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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