PDE11A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85919

Novus Biologicals, part of Bio-Techne
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NBP1-85919
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PDE11A Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: VVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLEDIESPVVKFTKSFELMSPKCSADAENSFKESMEKSSYSDWLINNSIAELVA

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PDE11A Antibody

Western Blot: PDE11A Antibody [NBP1-85919]

Western Blot: PDE11A Antibody [NBP1-85919]

Western Blot: PDE11A Antibody [NBP1-85919] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells) Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells)
Immunohistochemistry-Paraffin: PDE11A Antibody [NBP1-85919]

Immunohistochemistry-Paraffin: PDE11A Antibody [NBP1-85919]

Immunohistochemistry-Paraffin: PDE11A Antibody [NBP1-85919] - Staining of human prostate shows moderate cytoplasmic and membranous positivity in glandular cells.
Western Blot: PDE11A Antibody [NBP1-85919]

Western Blot: PDE11A Antibody [NBP1-85919]

Western Blot: PDE11A Antibody [NBP1-85919] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

Applications for PDE11A Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PDE11A

The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.

Long Name

Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A

Alternate Names

EC 3.1.4.35, EC 3.1.4.53

Gene Symbol

PDE11A

Additional PDE11A Products

Product Documents for PDE11A Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PDE11A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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