PDE11A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-19743

Novus Biologicals, part of Bio-Techne
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NBP2-19743
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PDE11A Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human PDE11A. The exact sequence is proprietary.

Localization

Cytoplasm; cytosol

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

105 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PDE11A Antibody

Western Blot: PDE11A Antibody [NBP2-19743]

Western Blot: PDE11A Antibody [NBP2-19743]

Western Blot: PDE11A Antibody [NBP2-19743] - Sample (30 ug of whole cell lysate) A: PC-3 7. 5% SDS PAGE gel, diluted at 1:1000.
Immunohistochemistry-Paraffin: PDE11A Antibody [NBP2-19743]

Immunohistochemistry-Paraffin: PDE11A Antibody [NBP2-19743]

Immunohistochemistry-Paraffin: PDE11A Antibody [NBP2-19743] - Immunohistochemical analysis of paraffin-embedded U87 xenograft, using antibody at 1:500 dilution.

Applications for PDE11A Antibody

Application
Recommended Usage

Immunohistochemistry

10 - 1:500

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: PDE11A

The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Long Name

Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A

Alternate Names

EC 3.1.4.35, EC 3.1.4.53

Gene Symbol

PDE11A

UniProt

Q9HCR9 (Human)

Additional PDE11A Products

Product Documents for PDE11A Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for PDE11A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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