PDE1C Antibody [PE]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-00157PE

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Product Datasheet / COA / SDS

View Available Conjugates

Conjugate

Catalog #

Unconjugated

NBP3-00157

Alexa Fluor 350

NBP3-00157AF350

Alexa Fluor 405

NBP3-00157AF405

Alexa Fluor 488

NBP3-00157AF488

Alexa Fluor 532

NBP3-00157AF532

Alexa Fluor 594

NBP3-00157AF594

Alexa Fluor 647

NBP3-00157AF647

Alexa Fluor 700

NBP3-00157AF700

Alexa Fluor 750

NBP3-00157AF750

Allophycocyanin

NBP3-00157APC

Biotin

NBP3-00157B

CoraFluor 1

NBP3-00157CL1

DyLight 350

NBP3-00157UV

DyLight 405

NBP3-00157V

DyLight 488

NBP3-00157G

DyLight 550

NBP3-00157R

DyLight 594

NBP3-00157DL594

DyLight 650

NBP3-00157C

DyLight 680

NBP3-00157FR

DyLight 755

NBP3-00157IR

FITC

NBP3-00157F

HRP

NBP3-00157H

Janelia Fluor 525

NBP3-00157JF525

Janelia Fluor 549

NBP3-00157JF549

Janelia Fluor 585

NBP3-00157JF585

Janelia Fluor 635

NBP3-00157JF635

Janelia Fluor 646

NBP3-00157JF646

Janelia Fluor 669

NBP3-00157JF669

mFluor Violet 450 SE

NBP3-00157MFV450

mFluor Violet 500 SE

NBP3-00157MFV500

mFluor Violet 610 SE

NBP3-00157MFV610

PerCP

NBP3-00157PCP

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry-Paraffin

Label

PE (Excitation = 488 nm, Emission = 575 nm)

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all PDE1C Antibodies »

Product Summary for PDE1C Antibody [PE]

Immunogen

Produced in rabbits immunized with purified, recombinant Human PDE1C (Uniprot#: Q8TAE4; Met1-Glu634)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for PDE1C Antibody [PE]

Application

Recommended Usage

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: PDE1C

PDE1C is a phosphodiesterase activated by the binding of calmodulin in the presence of calcium. Cyclic nucleotides are hydrolyzed and compartmentalized by a family of enzymes called phosphodiesterases. In mammals at least 11 different families of PDEs can be discriminated (PDE1-11) based on their kinetic properties and inhibition to various pharmacological agents. Three different PDE1 genes have been identified (PDE1A, PDE1B, PDE1C). The enzymes of the PDE1A and PDE1B have higher affinity for cGMP than for cAMP, where as, PDE1C has high affinity for both cAMP and cGMP. Calcium-Calmodulin stimulates the activity of each of these enzymes several-fold. The PDE1C gene codes a family of proteins (variants) that differ from each other at amino and carboxy termini of the protein. The tissue distribution of PDE1C is different from other PDE1 gene family members.

Long Name

Dual specificity Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C

Alternate Names

Cam-PDE 1C, Hcam3

Gene Symbol

PDE1C

Additional PDE1C Products

Product Documents for PDE1C Antibody [PE]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for PDE1C Antibody [PE]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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