PDGFR alpha Antibody (MM0004-8A89) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB110-60969

Novus Biologicals, part of Bio-Techne
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NB110-60969-0.025mg
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # MM0004-8A89

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

View all PDGF R alpha Antibodies »

Product Specifications

Immunogen

Human recombinant PDGFR alpha (N-terminal)

Specificity

No cross-reactivity is shown with human PDGF Receptor beta.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for PDGFR alpha Antibody (MM0004-8A89) - Azide and BSA Free

Immunohistochemistry-Paraffin: PDGFR alpha Antibody (MM0004-8A89) - Azide and BSA Free [NB110-60969]

Immunohistochemistry-Paraffin: PDGFR alpha Antibody (MM0004-8A89) - Azide and BSA Free [NB110-60969]

Immunohistochemistry-Paraffin: PDGF Receptor alpha Antibody (MM0004-8A89) [NB110-60969] - Formalin fixed and paraffin embedded normal human placenta tissue is subjected to mouse anti human PDGFR-a.

Applications for PDGFR alpha Antibody (MM0004-8A89) - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry

1:100-400

Immunohistochemistry-Paraffin

1:100-1:400

Western Blot

1:500-1:1000

Formulation, Preparation, and Storage

Purification

Protein G purified

Reconstitution

Reconstitute with sterilized PBS to a final concentration of 0.2 mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS, 0.025 mg size is provided in liquid form, PBS.

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: PDGF R alpha

Platelet derived growth factor receptor (PDGF Receptor) is a transmembrane glycoprotein of 170-185 kDa which undergoes homo or heterodimerization into complexes of alpha and beta subunits upon ligand binding, depending on the isoform of PDGF (PDGF AA, BB or AB) that binds. The phosphorylation of tyrosine residues in the now activated receptor can control multiple signaling events such as actin reorganization, transcription, cell growth, migration and differentiation, and also lead to activation of the Ras, Raf and ERK 1 and 2 pathway.

Long Name

Platelet-derived Growth Factor Receptor alpha

Alternate Names

CD140a, PDGFR alpha, PDGFRA

Entrez Gene IDs

5156 (Human)

Gene Symbol

PDGFRA

UniProt

P16234

Additional PDGF R alpha Products

Product Documents for PDGFR alpha Antibody (MM0004-8A89) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for PDGFR alpha Antibody (MM0004-8A89) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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