PEDFR/PNPLA2/ATGL Antibody (S08-3F5)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19942

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-19942-100ul
NBP3-19942-50ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S08-3F5

Concentration

0.3 mg/ml

View all PEDFR/PNPLA2 Antibodies »

Product Specifications

Immunogen

A synthetic peptide of human PEDFR/PNPLA2/ATGL (Uniprot # Q96AD5)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

55 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PEDFR/PNPLA2/ATGL Antibody (S08-3F5)

Western Blot: PEDFR/PNPLA2/ATGL Antibody (S08-3F5) [NBP3-19942]

Western Blot: PEDFR/PNPLA2/ATGL Antibody (S08-3F5) [NBP3-19942]

Western Blot: PEDFR/PNPLA2/ATGL Antibody (S08-3F5) [NBP3-19942] - Western blot detection of PEDFR/PNPLA2/ATGL in K562 cell lysates using NBP3-19942 (1:500 diluted). Predicted band size: 55kDa. Observed band size: 55kDa.

Applications for PEDFR/PNPLA2/ATGL Antibody (S08-3F5)

Application
Recommended Usage

Western Blot

1/1000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PEDFR/PNPLA2

Patatin-like phospholipase domain-containing protein 2 (PNPLA2), also known as adipose triglyceride lipase (ATGL), is a lipolytic enzyme required for mobilization of fatty acids from triglyceride stores in adipose tissue. Until recently, hormone-sensitive lipase (HSL) was the only enzyme known to hydrolyze triglycerides in mammalian adipose tissue. However, ATGL has now been shown to catalyze the initial step of triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets. Thus, ATGL and HSL coordinate to catabolize stored triglycerides in adipose tissue of mammals.

Defects in PNPLA2 can lead to neutral lipid storage disease with myopathy (NLSDM), a neutral lipid storage disorder with myopathy but without ichthyosis.

ATGL antibodies can serve as useful tools for adipocyte studies and research on triglyceride processing and fat storage.

Long Name

Pigment Epithelium-derived Factor Receptor/Patatin-like Phospholipase Domain-containing Protein 2

Alternate Names

ATGL, Desnutrin, IPLA2-zeta, PEDF R, PNPLA2, TTS2

Gene Symbol

PNPLA2

Additional PEDFR/PNPLA2 Products

Product Documents for PEDFR/PNPLA2/ATGL Antibody (S08-3F5)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PEDFR/PNPLA2/ATGL Antibody (S08-3F5)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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