PELP1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB110-40622

Novus Biologicals, part of Bio-Techne

Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Validated:

Human

Predicted:

Monkey (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot (Negative)

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all PELP1 Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 25 and 75 of human Proline-, Glutamic Acid-, Leucine-Rich Protein 1 (Modulator of Nongenomic Activity of Estrogen Receptor) using the numbering given in entry AAN41255.1 (GeneID 27

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PELP1 Antibody

Immunohistochemistry-Paraffin: PELP1 Antibody [NB110-40622]

Immunohistochemistry-Paraffin: PELP1 Antibody [NB110-40622]

Immunohistochemistry-Paraffin: PELP1 Antibody [NB110-40622] - Section of human testicular seminoma. Antibody: Affinity purified rabbit antiPELP1/MNAR used at a dilution of 1:1,000 (1ug/ml). Detection: DAB.
Immunoprecipitation: PELP1 Antibody [NB110-40622]

Immunoprecipitation: PELP1 Antibody [NB110-40622]

Immunoprecipitation: PELP1 Antibody [NB110-40622] - Detection of Human PELP1/MNAR by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-PELP1/MNAR antibody NB110-40622 used for IP at 3 mcg/mg lysate. PELP1/MNAR was also immunoprecipitated by other rabbit anti-PELP1/MNAR antibodies, which recognize downstream epitopes. Detection: Chemiluminescence with an exposure time of 1 second.

Applications for PELP1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:500- 1:2000

Immunohistochemistry-Paraffin

1:500- 1:2000

Immunoprecipitation

2-5 ug/mg lysate
Application Notes
Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: PELP1

PELP1/MNAR was identified as an SH2 domain interacting protein that interacts with Lck, c-Src, and other members of the Src kinase family. PELP1/MNAR appears to function as a general coregulator and interacts with multiple nuclear receptors and transcription factors. PELP1/MNAR has also been shown to participate in nongenomic signaling via an association with a multiprotein complex, the

Alternate Names

HMX3, MNARmodulator of nongenomic activity of estrogen receptor, Modulator of non-genomic activity of estrogen receptor, P160, proline and glutamic acid rich nuclear protein, proline, glutamate and leucine rich protein 1, proline, glutamic acid and leucine rich protein 1, proline-, glutamic acid- and leucine-rich protein 1, proline-, glutamic acid-, leucine-rich protein 1, Transcription factor HMX3

Entrez Gene IDs

27043 (Human)

Gene Symbol

PELP1

UniProt

AAN41255.1 (Human)

Additional PELP1 Products

Product Documents for PELP1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PELP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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