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Pentraxin 3/TSG-14 Antibody (10D9)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-26356

Recombinant monoclonal antibody expressed in HEK293F cells
Novus Biologicals, part of Bio-Techne
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NBP3-26356-100ul
NBP3-26356-50ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Flow Cytometry

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 10D9

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for Pentraxin 3/TSG-14 Antibody (10D9)

Immunogen

A synthesized peptide derived from Human Pentraxin 3/TSG-14 [UniProt P26022]

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Pentraxin 3/TSG-14 Antibody (10D9)

Pentraxin 3/TSG-14 Antibody (10D9)

Flow Cytometry: Pentraxin 3/TSG-14 Antibody (10D9) [NBP3-26356] -

Flow Cytometry: Pentraxin 3/TSG-14 Antibody (10D9) [NBP3-26356] - Overlay Peak curve showing A549 cells stained with Pentraxin 3/TSG-14 Antibody (10D9) (red line) at 1:100. The cells were incubated in 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*10^6 cells) for 45min at 4C. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG (H+L) at 1:200 dilution for 35min at 4C. Control antibody (green line) was rabbit IgG (1ug/1*10^6 cells) used under the same conditions. Acquisition of >10,000 events was performed.

Applications for Pentraxin 3/TSG-14 Antibody (10D9)

Application
Recommended Usage

Flow Cytometry

1:50-1:200
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl and 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -70C. Avoid freeze-thaw cycles.

Background: Pentraxin 3/TSG-14

Pentraxin 3 (PTX3) is the prototypic member of the long pentraxin family sharing the C-terminal domain with short pentraxins (C-reactive protein and serum amyloid P component) and containing a unique N-terminal domain. The protein is a soluble pattern recognition receptor and represents a nonredundant component of the humoral innate immunity against selected pathogens. PTX3 is rapidly produced and released at inflammatory sites by diverse cell types including monocytes/macrophages, endothelial cells, vascular smooth muscle cells, fibroblasts, and adipocytes. It interacts with several ligands, including growth factors, extracellular matrix components and selected pathogens. PTX3 has been implicated in vascular damage, angiogenesis, atherosclerosis, and restenosis.

Long Name

Tumor Necrosis Factor Stimulated Gene 14

Alternate Names

PTX3, TSG-14, TSG14

Gene Symbol

PTX3

Additional Pentraxin 3/TSG-14 Products

Product Documents for Pentraxin 3/TSG-14 Antibody (10D9)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Pentraxin 3/TSG-14 Antibody (10D9)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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