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Pentraxin 3/TSG-14 Antibody (SR1716)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21983

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
Availability
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NBP3-21983-100ul
NBP3-21983-50ul

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

Flow Cytometry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1716

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for Pentraxin 3/TSG-14 Antibody (SR1716)

Immunogen

A synthesized peptide derived from human Pentraxin 3/TSG-14 (Uniprot #: P26022)

Specificity

Detects endogenous levels of total Pentraxin 3/TSG-14

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

42 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Pentraxin 3/TSG-14 Antibody (SR1716)

Western Blot: Pentraxin 3/TSG-14 Antibody (SR1716) [NBP3-21983] -

Western Blot: Pentraxin 3/TSG-14 Antibody (SR1716) [NBP3-21983] - Western blot analysis using NBP3-21983 in HUVEC cell lysate.

Applications for Pentraxin 3/TSG-14 Antibody (SR1716)

Application
Recommended Usage

Flow Cytometry

1:50

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Pentraxin 3/TSG-14

Pentraxin 3 (PTX3) is the prototypic member of the long pentraxin family sharing the C-terminal domain with short pentraxins (C-reactive protein and serum amyloid P component) and containing a unique N-terminal domain. The protein is a soluble pattern recognition receptor and represents a nonredundant component of the humoral innate immunity against selected pathogens. PTX3 is rapidly produced and released at inflammatory sites by diverse cell types including monocytes/macrophages, endothelial cells, vascular smooth muscle cells, fibroblasts, and adipocytes. It interacts with several ligands, including growth factors, extracellular matrix components and selected pathogens. PTX3 has been implicated in vascular damage, angiogenesis, atherosclerosis, and restenosis.

Long Name

Tumor Necrosis Factor Stimulated Gene 14

Alternate Names

PTX3, TSG-14, TSG14

Gene Symbol

PTX3

Additional Pentraxin 3/TSG-14 Products

Product Documents for Pentraxin 3/TSG-14 Antibody (SR1716)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Pentraxin 3/TSG-14 Antibody (SR1716)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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