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Pentraxin 3/TSG-14 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-49595

Novus Biologicals, part of Bio-Techne
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NBP2-49595
NBP2-49595-25ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Rat (90%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for Pentraxin 3/TSG-14 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: GFDETLAFSGRLTGFNIWDSVLSNEEIRETGGAESCHIRGNIVGWGVTEIQPHGGAQYVS

Reactivity Notes

Mouse (85%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Pentraxin 3/TSG-14 Antibody

Immunohistochemistry-Paraffin: Pentraxin 3/TSG-14 Antibody [NBP2-49595]

Immunohistochemistry-Paraffin: Pentraxin 3/TSG-14 Antibody [NBP2-49595]

Immunohistochemistry-Paraffin: Pentraxin 3/TSG-14 Antibody [NBP2-49595] - Staining of human testis shows strong cytoplasmic positivity in cells in seminiferous ducts.
Immunohistochemistry-Paraffin: Pentraxin 3/TSG-14 Antibody [NBP2-49595]

Immunohistochemistry-Paraffin: Pentraxin 3/TSG-14 Antibody [NBP2-49595]

Immunohistochemistry-Paraffin: Pentraxin 3/TSG-14 Antibody [NBP2-49595] - Staining of human lung shows moderate positivity in secretion.
Immunohistochemistry-Paraffin: Pentraxin 3/TSG-14 Antibody [NBP2-49595]

Immunohistochemistry-Paraffin: Pentraxin 3/TSG-14 Antibody [NBP2-49595]

Immunohistochemistry-Paraffin: Pentraxin 3/TSG-14 Antibody [NBP2-49595] - Staining of human stomach shows moderate positivity in secretion.

Applications for Pentraxin 3/TSG-14 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Pentraxin 3/TSG-14

Pentraxin 3 (PTX3) is the prototypic member of the long pentraxin family sharing the C-terminal domain with short pentraxins (C-reactive protein and serum amyloid P component) and containing a unique N-terminal domain. The protein is a soluble pattern recognition receptor and represents a nonredundant component of the humoral innate immunity against selected pathogens. PTX3 is rapidly produced and released at inflammatory sites by diverse cell types including monocytes/macrophages, endothelial cells, vascular smooth muscle cells, fibroblasts, and adipocytes. It interacts with several ligands, including growth factors, extracellular matrix components and selected pathogens. PTX3 has been implicated in vascular damage, angiogenesis, atherosclerosis, and restenosis.

Long Name

Tumor Necrosis Factor Stimulated Gene 14

Alternate Names

PTX3, TSG-14, TSG14

Gene Symbol

PTX3

Additional Pentraxin 3/TSG-14 Products

Product Documents for Pentraxin 3/TSG-14 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Pentraxin 3/TSG-14 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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