Pepsinogen A4/PGA4 Antibody (021)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-90168

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 021

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Pepsinogen A4/PGA4 Antibodies »

Product Specifications

Immunogen

This antibody was obtained from a rabbit immunized with purified, recombinant Human Pepsinogen A4/PGA4 (Accession#: NP_001073276.1; Met1-Ala388).

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for Pepsinogen A4/PGA4 Antibody (021)

Immunohistochemistry-Paraffin: Pepsinogen A4/PGA4 Antibody (021) [NBP2-90168]

Immunohistochemistry-Paraffin: Pepsinogen A4/PGA4 Antibody (021) [NBP2-90168]

Immunohistochemistry-Paraffin: Pepsinogen A4/PGA4 Antibody (021) [NBP2-90168] - Immunochemical staining of human PGA in human gastric cancer with rabbit monoclonal antibody (1:1000, formalin-fixed paraffin embedded sections).

Applications for Pepsinogen A4/PGA4 Antibody (021)

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Pepsinogen A4/PGA4

Pepsins are aspartic proteases that are synthesized in the gastric mucosa and secreted into the stomach. They are released as zymogens called pepsinogens and then converted to active pepsins by the acidic pH of gastric juices. PGA-3, PGA-4, and PGA-5 are isozymogens of human Pepsinogen A, which differ in amino acid sequence by 2 - 4 residues. This recombinant human Pepsinogen A corresponds to PGA-4. Pepsins have optimal activity under conditions of acidic pH and are inhibited by pepstatin. Pepsin A has broad substrate specificity, but preferentially cleaves peptide bonds involving aromatic and aliphatic amino acids.

Alternate Names

Pepsin A-4, PGA4

Gene Symbol

PGA4

Additional Pepsinogen A4/PGA4 Products

Product Documents for Pepsinogen A4/PGA4 Antibody (021)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Pepsinogen A4/PGA4 Antibody (021)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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