Pepsinogen I Antibody (8003 (99/12))
Novus Biologicals, part of Bio-Techne | Catalog # NB100-62239
![Immunohistochemistry-Paraffin: Pepsinogen I Antibody (8003 (99/12)) - BSA Free [NB100-62239]](https://resources.bio-techne.com/images/products/Pepsinogen-I-Antibody-8003-99-12-Immunohistochemistry-Paraffin-NB100-62239-img0001.jpg "Immunohistochemistry-Paraffin: Pepsinogen I Antibody (8003 (99/12)) - BSA Free [NB100-62239]")
Conjugate
Catalog #
Key Product Details
Species Reactivity
Validated:
Human
Cited:
Human
Applications
Validated:
ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Radioimmunoassay
Cited:
Immunohistochemistry-Paraffin
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG1 Clone # 8003 (99/12)
Concentration
0.5 mg/ml
Product Specifications
Immunogen
Purified human pepsinogen 1
Localization
Secreted
Specificity
NB100-62239 recognises human Pepsinogen I, a zymogen or proenzyme secreted by Chief cells in the stomach. It is cleaved to form pepsin both in an autocatalytic fashion and by pepsin itself. In humans there are two related forms of pepsin, Pepsinogen I (also known as pepsinogen A), and Pepsinogen II (also known as Pepsinogen B or progastricsin).
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Scientific Data Images for Pepsinogen I Antibody (8003 (99/12))
Immunohistochemistry-Paraffin: Pepsinogen I Antibody (8003 (99/12)) - BSA Free [NB100-62239]
Immunohistochemistry-Paraffin: Pepsinogen I Antibody (8003 (99/12)) [NB100-62239] - Differentiation of pyloric-gland type to fundic glands. (A) HE-stained image, showing proliferation of atypical glands associated with mildly enlarged nuclei. (B) Differentiation into fundic glands (pepsinogen-1). Tumor glands are positive for pepsinogen-1. (C) Differentiation into fundic glands (H,K-ATPase). Similar to pepsinogen-1, H,K-ATPase-positive cells can be seen in tumor glands. From: Mitsuishi T, Hamatani S, Hirooka S, Fukasawa N, Aizawa D, Hara Y, et al. (2017)Applications for Pepsinogen I Antibody (8003 (99/12))
Application
Recommended Usage
ELISA
1:100-1:2000
Radioimmunoassay
1:100-1:2000
Formulation, Preparation, and Storage
Purification
Protein A purified
Formulation
PBS
Preservative
<0.1% Sodium Azide
Concentration
0.5 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: Pepsinogen I
Alternate Names
pepsinogen 3, group I (pepsinogen A)
Gene Symbol
PGA3
Additional Pepsinogen I Products
Product Documents for Pepsinogen I Antibody (8003 (99/12))
Product Specific Notices for Pepsinogen I Antibody (8003 (99/12))
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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