PGAM2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-38889

Novus Biologicals, part of Bio-Techne
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NBP2-38889
NBP2-38889-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PGAM2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: PMDEKHPYYNSISKERRYAGLK

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (86%), Rat (86%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PGAM2 Antibody

Western Blot: PGAM2 Antibody [NBP2-38889]

Western Blot: PGAM2 Antibody [NBP2-38889]

Western Blot: PGAM2 Antibody [NBP2-38889] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10
Lane 2: Human Skeletal muscle tissue
Immunohistochemistry-Paraffin: PGAM2 Antibody [NBP2-38889]

Immunohistochemistry-Paraffin: PGAM2 Antibody [NBP2-38889]

Immunohistochemistry-Paraffin: PGAM2 Antibody [NBP2-38889] - Staining of human liver shows low expression as expected.
Immunohistochemistry: PGAM2 Antibody [NBP2-38889]

Immunohistochemistry: PGAM2 Antibody [NBP2-38889]

Immunohistochemistry: PGAM2 Antibody [NBP2-38889] - Staining of human heart muscle shows strong positivity in myocytes.
View 1 more images

Applications for PGAM2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PGAM2

Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). This gene encodes muscle-specific PGAM subunit. Mutations in this gene cause muscle phosphoglycerate mutase eficiency, also known as glycogen storage disease X. (provided by RefSeq)

Alternate Names

BPG-dependent PGAM 2, EC 3.1.3.13, EC 5.4.2.1, EC 5.4.2.4, Muscle-specific phosphoglycerate mutase, PGAM-MGSD10, PGAMMMGC88743, phosphoglycerate mutase 2, phosphoglycerate mutase 2 (muscle), Phosphoglycerate mutase isozyme M

Gene Symbol

PGAM2

UniProt

P15259 (Human)

Additional PGAM2 Products

Product Documents for PGAM2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PGAM2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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