PGRMC1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-2841

Novus Biologicals, part of Bio-Techne
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NB100-2841
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA, Tumorsphere, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all PGRMC1 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-EPKDESARKND corresponding to C-Terminus according to NP_006658.1.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Theoretical MW

22 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PGRMC1 Antibody

Western Blot: PGRMC1 Antibody [NB100-2841]

Western Blot: PGRMC1 Antibody [NB100-2841]

Western Blot: PGRMC1 Antibody [NB100-2841] - Staining of Human Kidney (A), Liver (B) and Testes (C) lysate (35 ug protein in RIPA buffer). Antibody at 0.1 ug/mL. Detected by chemiluminescence.
Immunohistochemistry-Paraffin: PGRMC1 Antibody [NB100-2841]

Immunohistochemistry-Paraffin: PGRMC1 Antibody [NB100-2841]

Immunohistochemistry-Paraffin: PGRMC1 Antibody [NB100-2841] - Staining of paraffin embedded Human Testis. Antibody at 5 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
Tumorsphere: PGRMC1 Antibody [NB100-2841]

Tumorsphere: PGRMC1 Antibody [NB100-2841]

Tumorsphere: PGRMC1 Antibody [NB100-2841] - Staining of Mouse Testes lysate (35 ug protein in RIPA buffer). Antibody at 0.1 ug/mL. Detected by chemiluminescence.

Applications for PGRMC1 Antibody

Application
Recommended Usage

Immunohistochemistry

5 ug/mL

Immunohistochemistry-Paraffin

5 ug/mL

Peptide ELISA

Detection limit 1:4000

Western Blot

0.1 - 0.3 ug/mL
Application Notes
Western blot: Approx 24 kDa band observed in Human Kidney, Liver and Testis lysates, and approx 25 kDa in Mouse Testis lysates (calculated MW of 21.7kDa according to Human NP_006658.1 and Mouse NP_058063.2).
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: PGRMC1

Progesterone binding protein is a putative steroid membrane receptor. The protein is expressed predominantly in the liver and kidney.

Long Name

Progesterone Receptor Membrane Component 1

Alternate Names

HPR6.6, MPR, Progesterone Binding Protein

Entrez Gene IDs

10857 (Human); 53328 (Mouse)

Gene Symbol

PGRMC1

UniProt

O00264 (Human)

Additional PGRMC1 Products

Product Documents for PGRMC1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PGRMC1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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