PI 3-Kinase p85 beta Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-99487

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all PI 3-Kinase p85 beta Antibodies »

Product Summary for PI 3-Kinase p85 beta Antibody

Immunogen

Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human PI 3-Kinase p85 beta.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for PI 3-Kinase p85 beta Antibody

Immunohistochemistry-Paraffin: PI 3-Kinase p85 beta Antibody [NBP2-99487]

Immunohistochemistry-Paraffin: PI 3-Kinase p85 beta Antibody [NBP2-99487]

Immunohistochemistry-Paraffin: PI 3-Kinase p85 beta Antibody [NBP2-99487] - Immunochemical staining of human PI 3-Kinase in human testis with rabbit polyclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections.
Immunohistochemistry: PI 3-Kinase p85 beta Antibody [NBP2-99487]

Immunohistochemistry: PI 3-Kinase p85 beta Antibody [NBP2-99487]

Immunohistochemistry: PI 3-Kinase p85 beta Antibody [NBP2-99487] - Immunochemical staining of human PI 3-Kinase p85 in human duodenum with rabbit polyclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections.

Applications for PI 3-Kinase p85 beta Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PI 3-Kinase p85 beta

The enzyme phosphatidylinositol 3 kinase (PI3 kinase) is a lipid kinase that generates phosphatidylinositol 3, 4, 5-triphosphate in response to receptor activation in many signal transduction pathways. Class IA PI3Ks exist as a heterodimer of a catalytic 110 kDa (p110) and a regulatory p85 subunit (e.g. p85 beta). p85 beta is an adaptor molecule that regulates the activity of the catalytic p110 subunit by binding to phosphorylated receptor tyrosine kinases (RTKs) through its SH2 domain and mediating the interaction between p110 and the plasma membrane. p85 beta is necessary for insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.

Long Name

Phosphatidylinositol-3-kinase 85 kDa Regulatory Subunit beta

Alternate Names

p85-beta, PI 3Kinase p85 beta, PIK3R2

Gene Symbol

PIK3R2

Additional PI 3-Kinase p85 beta Products

Product Documents for PI 3-Kinase p85 beta Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for PI 3-Kinase p85 beta Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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