PICALM Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-19825

Novus Biologicals, part of Bio-Techne
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NBP2-19825
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Bovine (100%), Mouse (100%), Porcine (100%), Rat (100%), Rhesus Macaque (100%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PICALM Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human PICALM. The exact sequence is proprietary.

Localization

Membrane; clathrin-coated pit; Golgi apparatus; Cytoplasmic vesicle; clathrin-coated vesicle

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

71 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PICALM Antibody

Western Blot: PICALM Antibody [NBP2-19825]

Western Blot: PICALM Antibody [NBP2-19825]

Western Blot: PICALM Antibody [NBP2-19825] - Sample (30 ug of whole cell lysate) A: A549 7. 5% SDS PAGE gel, diluted at 1:2000.
Immunohistochemistry-Paraffin: PICALM Antibody [NBP2-19825]

Immunohistochemistry-Paraffin: PICALM Antibody [NBP2-19825]

Immunohistochemistry-Paraffin: PICALM Antibody [NBP2-19825] - Immunohistochemical analysis of paraffin-embedded Renal Tubule, using antibody at 1:250 dilution.

Applications for PICALM Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: PICALM

Assembly protein recruiting clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. May be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. Involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction.

Alternate Names

CALMclathrin assembly lymphoid-myeloid leukemia, Clathrin assembly lymphoid myeloid leukemia protein, CLTHphosphatidylinositol-binding clathrin assembly protein, LAP, phosphatidylinositol binding clathrin assembly protein

Gene Symbol

PICALM

UniProt

Q13492 (Human)

Additional PICALM Products

Product Documents for PICALM Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for PICALM Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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