PIGL Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86471

Novus Biologicals, part of Bio-Techne
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NBP1-86471
NBP1-86471-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PIGL Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: MKSREQGGRLGAESRTLLVIAHPDDEAMFFAPTVLGLARLRHWVYLLCFSAGNYYNQGETRKKELLQSCDVLGIPLSSVMIIDNRDFPDDPGMQWDTEHVARVLLQHIEVNGI

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PIGL Antibody

Immunocytochemistry/ Immunofluorescence: PIGL Antibody [NBP1-86471]

Immunocytochemistry/ Immunofluorescence: PIGL Antibody [NBP1-86471]

Immunocytochemistry/Immunofluorescence: PIGL Antibody [NBP1-86471] - Staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.
Immunohistochemistry-Paraffin: PIGL Antibody [NBP1-86471]

Immunohistochemistry-Paraffin: PIGL Antibody [NBP1-86471]

Immunohistochemistry-Paraffin: PIGL Antibody [NBP1-86471] - Staining of human gallbladder shows moderate cytoplasmic positivity in glandular cells.

Applications for PIGL Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PIGL

PIGL, also referred to as N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase, is approximately 29 kDa and 252 amino acids in length. PIGL localizes to the endoplasmic reticulum and is an important player the synthesis of GPI anchors as it catalyzes the second step in the reaction. Current research on PIGL is being performed relating to several diseases and disorders including congenital heart disease, babesiosis, ear anomalies syndrome, ichthyosiform dermatosis, malaria and sleeping sickness. PIGL has also been shown to have interactions with PIGA, PIGC, PIGH, DPM2, and GPLD1 in pathways such as GPI anchor biosynthesis and metabolic pathways.

Alternate Names

EC 3.5.1.89, N-acetylglucosaminylphosphatidylinositol deacetylase, N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase, phosphatidylinositol glycan anchor biosynthesis, class L, phosphatidylinositol glycan, class L, Phosphatidylinositol-glycan biosynthesis class L protein, PIG-L

Gene Symbol

PIGL

Additional PIGL Products

Product Documents for PIGL Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for PIGL Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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