PIM2 Antibody (SR1624)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22271

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22271-100ul
NBP3-22271-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1624

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all PIM2 Antibodies »

Product Summary for PIM2 Antibody (SR1624)

Immunogen

A synthesized peptide derived from human PIM2 (Uniprot #: Q9P1W9)

Specificity

Detects endogenous levels of total PIM2

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

37 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PIM2 Antibody (SR1624)

Western Blot: PIM2 Antibody (SR1624) [NBP3-22271] -

Western Blot: PIM2 Antibody (SR1624) [NBP3-22271] - Western blot analysis using NBP3-22271 in Raji cell lysate.

Applications for PIM2 Antibody (SR1624)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Immunoprecipitation

1:50

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PIM2

PIM2 belongs to a family of cytoplasmic serine/threonine protein kinases that consists of two other members, PIM1 and PIM3. Expression of this protein is regulated by hematopoietic cytokines. PIM2 is most abundantly expressed in hematopoietic tissues, spleen, thymus, and peripheral blood leukocytes, as well as in testis, small intestine, and colon. It is also highly expressed in human leukemic and lymphoma cell lines. The gene is also expressed in primary spermatocytes. The results suggest a role for PIM2 in proliferating cells as well as during meiosis. PIM2 is thought to be a mediator of p53 mediated apoptosis inhibition by interleukin 3, which supports its role in the formation of various tumours including lymphomas.

Long Name

Proviral Integration Site 2

Alternate Names

EC 2.7.11.1, pim-2 oncogene, pim-2h, proto-oncogene Pim-2 (serine threonine kinase), serine/threonine protein kinase pim-2, serine/threonine-protein kinase pim-2

Gene Symbol

PIM2

Additional PIM2 Products

Product Documents for PIM2 Antibody (SR1624)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for PIM2 Antibody (SR1624)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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