PIP5K2B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-13764

Novus Biologicals, part of Bio-Techne
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NBP2-13764
NBP2-13764-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (92%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PIP5K2B Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: EERAEDEECENDGVGGNLLCSYGTPP

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (88%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PIP5K2B Antibody

Immunohistochemistry-Paraffin: PIP5K2B Antibody [NBP2-13764]

Immunohistochemistry-Paraffin: PIP5K2B Antibody [NBP2-13764]

Immunohistochemistry-Paraffin: PIP5K2B Antibody [NBP2-13764] Staining of human cerebral cortex shows moderate positivity in neuropil.

Applications for PIP5K2B Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PIP5K2B

PIP5K2B, also known as Phosphatidylinositol 5-phosphate 4-kinase type-2 beta, has a 416 amino acid long isoform that is approximately 47 kDa and a short 281 amino acid isoform that is approximately 32 kDa. PIP5K2B interacts with p55 TNF receptor and is implicated in the biosynthesis of PIP2, which is a phospholipid component of the plasma membrane. Current research on PIP5K2B is being conducted in relation to several diseases and disorders including breast cancer and ataxia. Research has shown that PIP5K2B has interactions with BTK, RAC1, RNPS1, UBQLN4 and TNF Receptor I in pathways such as calcium signaling, cAMP signaling, regulation of actin cytoskeleton, and Inositol phosphate metabolism.

Alternate Names

1-phosphatidylinositol-4-phosphate kinase, 1-phosphatidylinositol-5-phosphate 4-kinase 2-beta, Diphosphoinositide kinase 2-beta, EC 2.7.1, EC 2.7.1.149, phosphatidylinositol-4-phosphate 5-kinase, type II, beta, Phosphatidylinositol-5-phosphate 4-kinase type II beta, phosphatidylinositol-5-phosphate 4-kinase type-2 beta, phosphatidylinositol-5-phosphate 4-kinase, type II, beta, PI(5)P 4-kinase type II beta, PI5P4KB, PIP4KII-beta, PIP5K2B, PIP5KIIB, PIP5KIIbeta, PTDINS(4)P-5-kinase, PtdIns(5)P-4-kinase isoform 2-beta

Gene Symbol

PIP4K2B

Additional PIP5K2B Products

Product Documents for PIP5K2B Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PIP5K2B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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