PKA R2 Antibody (6A9)

Novus Biologicals, part of Bio-Techne | Catalog # H00005576-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 6A9

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PKA R2 Antibodies »

Product Specifications

Immunogen

PRKAR2A (AAH02763, 1 a.a. ~ 105 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MSHIQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARAPASVLPAATPRQSLGHPPPEPGPDRVADAKGDSESEEDEDLEVPVPSRFNRRVSVCAETY

Localization

Cytoplasmic and Plasma membrane

Specificity

PRKAR2A - protein kinase, cAMP-dependent, regulatory, type II, alpha

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for PKA R2 Antibody (6A9)

Western Blot: PKA R2 Antibody (6A9) [H00005576-M01]

Western Blot: PKA R2 Antibody (6A9) [H00005576-M01]

Western Blot: PKA R2 Antibody (6A9) [H00005576-M01] - PRKAR2A monoclonal antibody (M01), clone 6A9 Analysis of PRKAR2A expression in HeLa.
Immunocytochemistry/ Immunofluorescence: PKA R2 Antibody (6A9) [H00005576-M01]

Immunocytochemistry/ Immunofluorescence: PKA R2 Antibody (6A9) [H00005576-M01]

Immunocytochemistry/Immunofluorescence: PKA R2 Antibody (6A9) [H00005576-M01] - Analysis of monoclonal antibody to PRKAR2A on HeLa cell . Antibody concentration 10 ug/ml.
Immunohistochemistry-Paraffin: PKA R2 Antibody (6A9) [H00005576-M01]

Immunohistochemistry-Paraffin: PKA R2 Antibody (6A9) [H00005576-M01]

Immunohistochemistry-Paraffin: PKA R2 Antibody (6A9) [H00005576-M01] - Analysis of monoclonal antibody to PRKAR2A on formalin-fixed paraffin-embedded human salivary gland. Antibody concentration 3 ug/ml.
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Applications for PKA R2 Antibody (6A9)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has been used for ELISA, IF and IHC-P.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: PKA R2

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER).

Alternate Names

protein kinase, cAMP-dependent, regulatory, type II, alpha, RII-alpha subunit

Entrez Gene IDs

5576 (Human)

Gene Symbol

PRKAR2A

OMIM

176910 (Human)

UniProt

AAH02763 (Human)

Additional PKA R2 Products

Product Documents for PKA R2 Antibody (6A9)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PKA R2 Antibody (6A9)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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