PKC beta 2 Antibody (N11-S)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-08202

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-08202
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Rabbit IgG Clone # N11-S

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all PKC beta 2 Antibodies »

Product Specifications

Immunogen

Peptide derived from C-terminal sequence of human PKC beta 2. Antibody recognizes the epitope located between Asn663 - Lys 672.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

This antibody is immunoaffinity purified with immunogenic peptide as a ligand.

Scientific Data Images for PKC beta 2 Antibody (N11-S)

Western Blot: PKC beta 2 Antibody (N11-S) [NBP3-08202]

Western Blot: PKC beta 2 Antibody (N11-S) [NBP3-08202]

Western Blot: PKC beta 2 Antibody (N11-S) [NBP3-08202] - Western blot of PKC beta 2 in mouse brain crude lysate (50ug of protein loaded.
Immunocytochemistry/ Immunofluorescence: PKC beta 2 Antibody (N11-S) [NBP3-08202]

Immunocytochemistry/ Immunofluorescence: PKC beta 2 Antibody (N11-S) [NBP3-08202]

Immunocytochemistry/Immunofluorescence: PKC beta 2 Antibody (N11-S) [NBP3-08202] - Representative pictures of PKC beta 2 expression in HEK293 cells, visualized with clonal rabbit anti-PKC beta 2 monospecific antibody. Primary antibody dilution - 1:200.
Immunocytochemistry/ Immunofluorescence: PKC beta 2 Antibody (N11-S) [NBP3-08202]

Immunocytochemistry/ Immunofluorescence: PKC beta 2 Antibody (N11-S) [NBP3-08202]

Immunocytochemistry/Immunofluorescence: PKC beta 2 Antibody (N11-S) [NBP3-08202] - Representative pictures of PKC beta 2 expression in HEK293 cells, visualized with clonal rabbit anti-PKC beta 2 monospecific antibody. Primary antibody dilution - 1:200.

Applications for PKC beta 2 Antibody (N11-S)

Application
Recommended Usage

ELISA

1:20000-1:100000

Western Blot

1:10000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

20 mM Tris-HCl, pH 8.0, 10 mg/ml BSA

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: PKC beta 2

Members of the Protein Kinase C (PKC) family are serine/threonine protein kinases that play a key regulatory role in a number of cellular functions including cell growth and differentiation, hormone secretion, and gene expression. Multiple genes and alternative splicing result in three subfamilies, which differ in their co-factor requirements: conventional PKC isoforms (alpha, beta 1, beta 2, and gamma) which require calcium and phosphatidylserine (PS), diacylglycerol (DAG) or phorbol esters for activation; novel isoforms (delta, epsilon, eta, and theta), which are calcium-independent but are still regulated by PS, DAG, or phorbol esters; and atypical isoforms (iota/lambda and zeta), which are calcium-independent and do not require PS, DAG, or phorbol esters for activation. PKC beta 2 regulation of c-myc expression has been shown to suppress insulin gene transcription in pancreatic beta-cells implicating PKC beta 2 for some of the beta-cell glucose toxicity found in diabetes.

Long Name

Protein Kinase C beta 2

Alternate Names

PKCB;PKCbeta;PKC-beta;PKCI(2);PRKCB;PRKCB1;PRKCB2;Protein kinase C beta type

Gene Symbol

PRKCB

Additional PKC beta 2 Products

Product Documents for PKC beta 2 Antibody (N11-S)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PKC beta 2 Antibody (N11-S)

This antibody is immunoaffinity purified with immunogenic peptide as a ligand.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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