PKHD1 Antibody (8G12A1)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-27118

Novus Biologicals, part of Bio-Techne
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NBP3-27118-0.025ml
NBP3-27118-0.1ml
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Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 8G12A1

Concentration

1 mg/ml

View all PKHD1 Antibodies »

Product Summary for PKHD1 Antibody (8G12A1)

Immunogen

Purified recombinant fragment of mouse PKHD1 (AA: 3878-4060) expressed in E. Coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

445 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PKHD1 Antibody (8G12A1)

Flow Cytometry: PKHD1 Antibody (8G12A1) [NBP3-27118] -

Flow Cytometry: PKHD1 Antibody (8G12A1) [NBP3-27118] - Analysis of Hela cells using PKHD1 Rat mAb (green) and negative control (red).

Immunohistochemistry: PKHD1 Antibody (8G12A1) [NBP3-27118] -

Immunohistochemistry: PKHD1 Antibody (8G12A1) [NBP3-27118] - Analysis of paraffin-embedded esophageal cancer tissues using PKHD1 Rat mAb with DAB staining.

ELISA: PKHD1 Antibody (8G12A1) [NBP3-27118] -

ELISA: PKHD1 Antibody (8G12A1) [NBP3-27118] - Black line: Control Antigen (100 ng); Purple line: Antigen (10 ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng)
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Applications for PKHD1 Antibody (8G12A1)

Application
Recommended Usage

ELISA

1:10000

Flow Cytometry

1:200 - 1:400

Immunocytochemistry/ Immunofluorescence

1:200 - 1:1000

Immunohistochemistry

1:200 - 1:1000

Immunohistochemistry-Paraffin

1:200 - 1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PKHD1

Found mainly in the cytoplasm and plasma membrane, PKHD1 plays an important role in protein binding and receptor activity. The protein encoded by PKHD1 has a single transmembrane (TM) spanning domain and various copies of an immunoglobulin-like plexin-transcription-factor domain. More specifically, these transcripts encode products which lack the TM and may be secreted. In humans, PKHD1 is highly expressed in the kidney by acting as a receptor protein in the cortical and medullary collecting ducts. Diseases associated with PKHD1 include polycystic kidney and hepatic disease, liver disease, neoplasia, fibrosis, cancer, adenocarcinoma and prostate cancer.

Alternate Names

polycystic kidney and hepatic disease 1 (autosomal recessive)

Gene Symbol

PKHD1

Additional PKHD1 Products

Product Documents for PKHD1 Antibody (8G12A1)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for PKHD1 Antibody (8G12A1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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