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Key Product Details

Species Reactivity

Mouse

Applications

CyTOF-ready, Flow Cytometry, Immunohistochemistry

Label

DyLight 594 (Excitation = 593 nm, Emission = 618 nm)

Antibody Source

Recombinant Monoclonal Rat IgG2A Clone # 772417

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Chinese hamster ovary cell line CHO-derived recombinant mouse Plexin B2
Leu20-Trp1029
Accession # B2RXS4

Specificity

Detects mouse Plexin B2 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human Plexin B2 is observed.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2A

Applications for Plexin B2 Antibody (772417) [DyLight 594]

Application
Recommended Usage

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Plexin B2

Plexin B2, also known by its gene name PLXNB2, has 1,838 amino acids and is approximately 205kDa. Plexin B2 is a member of the Plexin family, and localizes to the cell membrane as a transmembrane receptor. Plexin B2 is a receptor for Semaphorins, such as SEMA4C, SEMA4D and SEMA4G, and is implicated in cell migration, cell-cell signaling, and axon guidance. Current research on Plexin B2 is being performed in relation to several diseases and disorders including leukemia, neuronitis and Situs inversus. Plexin B2 has also been shown to have interactions with MET, PFDN1, HMOX2, MST1R, and MLF1IP in the axon guidance pathway.

Alternate Names

MM1, PLEXB2, PLXNB2

Gene Symbol

PLXNB2

Additional Plexin B2 Products

Product Documents for Plexin B2 Antibody (772417) [DyLight 594]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Plexin B2 Antibody (772417) [DyLight 594]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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