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PNMT Antibody (CL11434)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21193

Novus Biologicals, part of Bio-Techne
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NBP3-21193-100ul
NBP3-21193-25ul

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (90%), Rat (92%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL11434

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence of P11086. Actual immunogen sequence is proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for PNMT Antibody (CL11434)

Immunohistochemistry-Paraffin: PNMT Antibody [NBP3-21193] -

Immunohistochemistry-Paraffin: PNMT Antibody [NBP3-21193] -

Analysis in human adrenal gland and kidney tissues using NBP3-21193 antibody. Corresponding PNMT RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: PNMT Antibody [NBP3-21193] -

Immunohistochemistry-Paraffin: PNMT Antibody [NBP3-21193] -

Staining of human Kidney shows no positivity in cells in seminiferous ducts as expected.
Immunohistochemistry-Paraffin: PNMT Antibody [NBP3-21193] -

Immunohistochemistry-Paraffin: PNMT Antibody [NBP3-21193] -

Staining of human Cerebral cortex shows very weak cytoplasmic positivity in neuronal cells.

Applications for PNMT Antibody (CL11434)

Application
Recommended Usage

Immunohistochemistry

1:200-1:500

Immunohistochemistry-Paraffin

1:200-1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PNMT

The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production.

Long Name

Phenylethanolamine N-Methyltransferase

Alternate Names

Noradrenaline N-methyltransferase, PENT, PNMTase

Gene Symbol

PNMT

Additional PNMT Products

Product Documents for PNMT Antibody (CL11434)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PNMT Antibody (CL11434)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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