PNR/NR2E3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-22466

Novus Biologicals, part of Bio-Techne
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NBP2-22466-0.025mg
NBP2-22466
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Key Product Details

Species Reactivity

Validated:

Human, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1 mg/ml

View all PNR/NR2E3 Antibodies »

Product Summary for PNR/NR2E3 Antibody

Immunogen

Synthetic peptide corresponding to residues R(392) K T I G N T P M E K L L C D M F K N(410) of human PNR.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PNR/NR2E3 Antibody

Western Blot: PNR/NR2E3 Antibody [NBP2-22466]

Western Blot: PNR/NR2E3 Antibody [NBP2-22466]

Western Blot: PNR/NR2E3 Antibody [NBP2-22466] - Analysis of PNR in whole rat eye extracts.

Applications for PNR/NR2E3 Antibody

Application
Recommended Usage

Western Blot

2 ug/ml
Application Notes
WB: Detects an approx. 42 kDa protein representing PNR from rat tissue extracts.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS with 1 mg/ml BSA

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: PNR/NR2E3

Photoreceptor-specific nuclear receptor (PNR), a NR2 Hepatocyte NF4-Like Receptor, has been suggested to affect cone cell proliferation in eye development. It has been shown to have a role in determining photoreceptor phenotype during human retinogenesis. In RD7 mice, a deletion in PNR results in hereditary retinal dysplasia and degeneration. A homozygous missense mutation in PNR has been linked to retinitis pigmentosa in Crypto-Jews of Belmonte. Two alternatively spliced isoforms have been documented. PNR is expressed in the retina. ESTs have been isolated from cancerous human lung, colon, and ovary, and from normal human eye.

Long Name

Photoreceptor-specific Nuclear Receptor

Alternate Names

NR2E3, RNR

Entrez Gene IDs

23958 (Mouse)

Gene Symbol

NR2E3

Additional PNR/NR2E3 Products

Product Documents for PNR/NR2E3 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for PNR/NR2E3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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