Polycystin 2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-80944

Novus Biologicals, part of Bio-Techne
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NBP1-80944
NBP1-80944-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (96%), Rat (96%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Polycystin 2 Antibodies »

Product Summary for Polycystin 2 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: REDLDLDHSSLPRPMSSRSFPRSLDDSEEDDDEDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGVAEDERLGRDSEIHREQMERLVREELERWESDDAASQISH

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Polycystin 2 Antibody

Immunocytochemistry/ Immunofluorescence: Polycystin 2 Antibody [NBP1-80944]

Immunocytochemistry/ Immunofluorescence: Polycystin 2 Antibody [NBP1-80944]

Immunocytochemistry/Immunofluorescence: Polycystin 2 Antibody [NBP1-80944] - Staining of human cell line BJ shows localization to endoplasmic reticulum. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: Polycystin 2 Antibody [NBP1-80944]

Immunohistochemistry-Paraffin: Polycystin 2 Antibody [NBP1-80944]

Immunohistochemistry-Paraffin: Polycystin 2 Antibody [NBP1-80944] - Staining of human kidney shows positivity in a subset of renal tubules.

Applications for Polycystin 2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Polycystin 2

Polycystin 2 is encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN.

Alternate Names

APKD2, Autosomal dominant polycystic kidney disease type II protein, MGC138466, MGC138468, PC2, Pc-2, PKD4, polycystic kidney disease 2 (autosomal dominant), Polycystic kidney disease 2 protein, polycystin-2, polycystwin, R48321, transient receptor potential cation channel, subfamily P, member 2, TRPP2

Entrez Gene IDs

5311 (Human)

Gene Symbol

PKD2

UniProt

Q13563 (Human)

Additional Polycystin 2 Products

Product Documents for Polycystin 2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Polycystin 2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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