PON1 Antibody (4G8D3) [DyLight 488]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-23610G

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Flow Cytometry, ICC/IF (Negative), Immunohistochemistry, Western Blot

Label

DyLight 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Monoclonal Mouse IgG1 Clone # 4G8D3

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all PON1 Antibodies »

Product Summary for PON1 Antibody (4G8D3) [DyLight 488]

Immunogen

Partial recombinant human PON1 (between residues 1-200) expressed in E. coli [Uniprot P27169]

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for PON1 Antibody (4G8D3) [DyLight 488]

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

ICC/IF (Negative)

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Ammonium sulfate precipitation

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: PON1

In humans, the paraoxonase (PON) gene family in humans has three members; PON1, PON2, and PON3. PON1 is synthesized primarily in the liver, and a portion is secreted into the plasma, where it is associated with high density lipoproteins (HDL). PON1 hydrolyzes the active metabolites of several other organophosphorus insecticides (e.g., chlorpyrifos oxon, diazoxon), as well as nerve agents such as sarin, soman and VX (lethal nerve agent). The PON1 polymorphism may be responsible for neurodegeneration and considered to be an independent risk factor for Parkinson's disease.

Long Name

Paraoxonase 1

Alternate Names

ESA, K-45

Gene Symbol

PON1

Additional PON1 Products

Product Documents for PON1 Antibody (4G8D3) [DyLight 488]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PON1 Antibody (4G8D3) [DyLight 488]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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