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PON1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-19893

Novus Biologicals, part of Bio-Techne
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NBP2-19893

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Mouse

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Full length human PON1 Recombinant protein.

Reactivity Notes

Rat (81%), Pig (84%), Rabbit (85%), Bovine (82%).

Localization

Secreted; extracellular space

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

40 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PON1 Antibody

Western Blot: PON1 Antibody [NBP2-19893]

Western Blot: PON1 Antibody [NBP2-19893]

Western Blot: PON1 Antibody [NBP2-19893] - . Human tissue extracts (30 ug) was separated by 10% SDS-PAGE, and the membrane was blotted with PON1 antibody diluted at 1:1000.
Immunohistochemistry-Paraffin: PON1 Antibody [NBP2-19893]

Immunohistochemistry-Paraffin: PON1 Antibody [NBP2-19893]

Immunohistochemistry-Paraffin: PON1 Antibody [NBP2-19893] - Analysis of mouse liver. PON1 antibody diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Applications for PON1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: PON1

The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3. [provided by RefSeq]

Long Name

Paraoxonase 1

Alternate Names

ESA, K-45

Gene Symbol

PON1

UniProt

Additional PON1 Products

Product Documents for PON1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PON1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.