Porimin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-27172

Novus Biologicals, part of Bio-Techne
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NBP2-27172
NBP2-27172SS
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Key Product Details

Species Reactivity

Validated:

Rat

Predicted:

Orangutan (94%), Rhesus Macaque (94%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all Porimin Antibodies »

Product Summary for Porimin Antibody

Immunogen

179 SRRGIRYRSIDEHDAII 195

Reactivity Notes

The amino acid sequence used as immunogen is 94% in White-cheeked Gibbon, and 88% homologous in Equine, and Chicken.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Porimin Antibody

Western Blot: Porimin Antibody [NBP2-27172]

Western Blot: Porimin Antibody [NBP2-27172]

Western Blot: Porimin Antibody [NBP2-27172] - Lysate from mouse NIH3T3 cells in the 1) absence and 2) presence of immunizing peptide probed with Tmem123 antibody at 7 ug/ml. goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.

Applications for Porimin Antibody

Application
Recommended Usage

Western Blot

5-8ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

0.2 ml PBS and 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Porimin

Transmembrane protein 123, or Tmem123, is a single-pass type I membrane protein and belongs to the CD164 family. Tmem123 acts as a novel marker for DC maturation. DCs are also known as professional antigen-presenting cells. It is reported that the Tmem123 molecule may be closely associated with the cell surface expression of CD40. It was also reported previously that Tmem123 protein may also be responsible for oncotic cell death, which is characterized by cell swelling, organelle swelling, vacuolization, increased membrane permeability and cell adhesion.

Long Name

Pro-Oncosis Receptor Inducing Membrane Injury

Alternate Names

KCT3, TMEM123

Gene Symbol

TMEM123

UniProt

Q91Z22 (Mouse)

Additional Porimin Products

Product Documents for Porimin Antibody

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Certificate of Analysis

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Product Specific Notices for Porimin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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