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POU3F3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-49508

Novus Biologicals, part of Bio-Techne
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NBP2-49508
NBP2-49508-25ul

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: GGAQSLVHPGLVRGDTPELAEHHHHH

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for POU3F3 Antibody

Immunohistochemistry-Paraffin: POU3F3 Antibody [NBP2-49508]

Immunohistochemistry-Paraffin: POU3F3 Antibody [NBP2-49508]

Immunohistochemistry-Paraffin: POU3F3 Antibody [NBP2-49508] - Analysis in human kidney and pancreas tissues. Corresponding RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: POU3F3 Antibody [NBP2-49508]

Immunohistochemistry-Paraffin: POU3F3 Antibody [NBP2-49508]

Immunohistochemistry-Paraffin: POU3F3 Antibody [NBP2-49508] - Staining of human pancreas shows no positivity in exocrine glandular cells as expected.
Immunohistochemistry-Paraffin: POU3F3 Antibody [NBP2-49508]

Immunohistochemistry-Paraffin: POU3F3 Antibody [NBP2-49508]

Immunohistochemistry-Paraffin: POU3F3 Antibody [NBP2-49508] - Staining of human kidney shows moderate to strong nuclear positivity in cells in distal tubules.

Applications for POU3F3 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: POU3F3

POU3F3, also known as POU Class 3 Homeobox 3, is a transcription factor that is primarily expressed in the brain and CNS. POU3F3 interacts with SOX4 and SOX11, and is implicated in the development of neurons. Current research surrounding POU3F3 has shown potential linkages with neuronitis and cerebritis. POU3F3 has also been shown to interact with POU3F4, CAV1, SOX10, and GADD34.

Alternate Names

brain-1, Brain-specific homeobox/POU domain protein 1, Brn-1, BRN1brn-1, Oct-8, Octamer-binding protein 8, Octamer-binding transcription factor 8, OTF-8, OTF8oct-8, POU class 3 homeobox 3, POU domain class 3, transcription factor 3, POU domain, class 3, transcription factor 3

Gene Symbol

POU3F3

Additional POU3F3 Products

Product Documents for POU3F3 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for POU3F3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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