Skip to main content

PP2C beta/PPM1B Antibody (OTI3C9)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-45383

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
Loading...
NBP2-45383
Conjugate
Catalog #

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # OTI3C9

Concentration

1 mg/ml

Product Specifications

Immunogen

Full length human recombinant protein of human PPM1B (NP_002697) produced in HEK293T cell.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Theoretical MW

52.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PP2C beta/PPM1B Antibody (OTI3C9)

Western Blot: PP2C beta/PPM1B Antibody (OTI3C9) [NBP2-45383]

Western Blot: PP2C beta/PPM1B Antibody (OTI3C9) [NBP2-45383]

Western Blot: PP2C beta/PPM1B Antibody (OTI3C9) [NBP2-45383] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PPM1B.
Immunocytochemistry/ Immunofluorescence: PP2C beta/PPM1B Antibody (OTI3C9) [NBP2-45383]

Immunocytochemistry/ Immunofluorescence: PP2C beta/PPM1B Antibody (OTI3C9) [NBP2-45383]

Immunocytochemistry/Immunofluorescence: PP2C beta/PPM1B Antibody (OTI3C9) [NBP2-45383] - Analysis of COS7 cells transiently transfected by pCMV6-ENTRY PPM1B.
Flow Cytometry: PP2C beta/PPM1B Antibody (OTI3C9) [NBP2-45383]

Flow Cytometry: PP2C beta/PPM1B Antibody (OTI3C9) [NBP2-45383]

Flow Cytometry: PP2C beta/PPM1B Antibody (OTI3C9) [NBP2-45383] - Analysis of HEK293T cells transfected with either RC212918 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by PPM1B antibody, and then analyzed by flow cytometry.

Applications for PP2C beta/PPM1B Antibody (OTI3C9)

Application
Recommended Usage

Flow Cytometry

1:100

Immunocytochemistry/ Immunofluorescence

1:100

Western Blot

1:1000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: PP2C beta/PPM1B

PPM1B is encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.

Long Name

Protein Phosphatase 2C beta

Alternate Names

Pp2c2, PP2CB, PPM1B

Gene Symbol

PPM1B

Additional PP2C beta/PPM1B Products

Product Documents for PP2C beta/PPM1B Antibody (OTI3C9)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PP2C beta/PPM1B Antibody (OTI3C9)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Loading...
Loading...
Loading...
Loading...
Loading...