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PP2C gamma/PPM1G Antibody (S05-8C4)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19743

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
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NBP3-19743-100ul
NBP3-19743-50ul

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S05-8C4

Concentration

0.3 mg/ml

Product Summary for PP2C gamma/PPM1G Antibody (S05-8C4)

Immunogen

Recombinant protein of human PP2C gamma/PPM1G (Uniprot # O15355)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

75 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PP2C gamma/PPM1G Antibody (S05-8C4)

Western Blot: PP2C gamma/PPM1G Antibody (S05-8C4) [NBP3-19743]

Western Blot: PP2C gamma/PPM1G Antibody (S05-8C4) [NBP3-19743]

Western Blot: PP2C gamma/PPM1G Antibody (S05-8C4) [NBP3-19743] - Western blot detection of PP2C gamma/PPM1G in K562 (Lane 1), Rat Brain (Lane 2), C6 (Lane 3), 3T3 (Lane 4), Hela (Lane 5) cell lysates using NBP3-19743 (1:1000 diluted). Predicted band size: 59kDa. Observed band size: 75kDa.

Applications for PP2C gamma/PPM1G Antibody (S05-8C4)

Application
Recommended Usage

Western Blot

1/2000-1/10000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PP2C gamma

PPM1G is encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.

Long Name

Protein Phosphatase 2C gamma

Alternate Names

PP2CG, PPM1C, PPM1G, PPP2CG

Gene Symbol

PPM1G

Additional PP2C gamma Products

Product Documents for PP2C gamma/PPM1G Antibody (S05-8C4)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PP2C gamma/PPM1G Antibody (S05-8C4)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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