PPAP2C Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-25062

Novus Biologicals, part of Bio-Techne
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NBP3-25062
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PPAP2C Antibodies »

Product Specifications

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein PPAP2C using the following amino acid sequence: PYKRGFYCGDDSIRYPYRPDTIT

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PPAP2C Antibody

PPAP2C Antibody Immunocytochemistry/Immunofluorescence: PPAP2C Antibody [NBP3-25062]

Immunocytochemistry/Immunofluorescence: PPAP2C Antibody [NBP3-25062]

Staining of human cell line U-251MG shows localization to plasma membrane.

Applications for PPAP2C Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 µg/ml
Application Notes
For ICC/IF, we recommend using a combination of PFA and Triton X-100. This will give you the optimal results for your experiments.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PPAP2C

PPAP2C, also referred to as Phosphatidic Acid Phosphatase Type 2C, has a canonical sequence that is 288 amino acids long and approximately 32kDa, and two other isoforms that are 309 and 232 amino acids in length, respectively. PPAP2C is an enzyme that hydrolyzes S1P, C1P and LPA, and catalyzes the conversion of phosphatidic acid to diacylglycerol. Current research surrounding PPAP2C has shown a possible linkage with strabismus and gastroenteritis. PPAP2C has also been shown to interact with APLP1, BAG6, GALC, MLH1, and UNC119 in pathways such as triacylglyceride synthesis, sphingolipid metabolism, triacylglycerol biosynthesis, and Fc gamma R-mediated phagocytosis.

Alternate Names

EC 3.1.3.4, LPP2PAP2-g, PAP2c, PAP-2clipid phosphate phosphohydrolase 2, PAP2-G, PAP2-gamma, Phosphatidate phosphohydrolase type 2c, Phosphatidic acid phosphatase 2c, phosphatidic acid phosphatase type 2C, phosphatidic acid phosphohydrolase type 2c, type-2 phosphatidic acid phosphatase-gamma

Gene Symbol

PLPP2

Additional PPAP2C Products

Product Documents for PPAP2C Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PPAP2C Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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