PPIG Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-19117

Novus Biologicals, part of Bio-Techne
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NBP1-19117
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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.2 mg/ml

View all PPIG Antibodies »

Product Summary for PPIG Antibody

Immunogen

The immunogen recognized by this antibody maps to a region between residue 450 and 500 of human SR-cyclophilin (Peptidyl-prolyl isomerase G) using the numbering given in entry NP_004783.2 (GeneID 9360).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PPIG Antibody

Western Blot: PPIG Antibody [NBP1-19117]

Western Blot: PPIG Antibody [NBP1-19117]

Western Blot: PPIG Antibody [NBP1-19117] - Whole cell lysate (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-SRcyp antibody used for WB at 0.04 ug/ml (A) and 1 ug/ml (B) and used for IP at 3 ug/mg lysate. SRcyp wasalso immunoprecipitated by rabbit anti-SRcyp antibody, which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 30seconds (A) and 3 seconds (B).
Immunohistochemistry: PPIG Antibody [NBP1-19117]

Immunohistochemistry: PPIG Antibody [NBP1-19117]

Immunohistochemistry: PPIG Antibody [NBP1-19117] - Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti- SRcyp used at a dilution of 1:200 (1ug/ml). Detection: DAB

Applications for PPIG Antibody

Application
Recommended Usage

Immunohistochemistry

1:100 - 1:500

Immunohistochemistry-Paraffin

1:100 - 1:500

Immunoprecipitation

2-5 ug/mg lysate

Western Blot

1:2000-1:10000
Application Notes
Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: PPIG

SR cyclophilin (SRcyp) is also known as peptidyl-prolyl cis-trans isomerase G. Cyclophilins are peptidyl-prolyl isomerases (PPIases) that accelerate the folding of proteins by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. The function of cyclophilins is poorly understood, but their function has been linked to multiple cellular processes such as protein folding, trafficking, and chaperone activity. SRcyp is a member of the Moca family of nuclear cyclophilins and is phosphorylated in a cell cycle dependent manner. There is evidence that SRcyp may be involved in the regulation of gene expression and mRNA splicing. Alternative names for SRcyp include PPIase G, rotamase G, cyclophilin G, clk-associating RS-cyclophilin, CARS-cyclophilin, SR-cyp, CASP10, and PPIG.

Alternate Names

CARS-cyclophilin, CARS-CypPPIase G, CASP10, Clk-associating RS-cyclophilin, Cyclophilin G, CYP, EC 5.2.1.8, MGC133241, peptidyl-prolyl cis-trans isomerase G, Peptidyl-prolyl isomerase G, peptidylprolyl isomerase G (cyclophilin G), peptidyl-prolyl isomerase G (cyclophilin G), Rotamase G, SCAF10, SR-cyclophilin, SRCyp, SR-cyp, SR-related CTD-associated factor 10

Entrez Gene IDs

9360 (Human)

Gene Symbol

PPIG

UniProt

NP_004783.2 (Human)

Additional PPIG Products

Product Documents for PPIG Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for PPIG Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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